Inhibitory effect of statins on fetal bovine serum??induced proliferation of rat cultured mesangial cells and correlation between their inhibitory effect and transport …
Abstract Mesangial cells play an important role in physiologic functions, including the regulation of glomerular filtration, and as a pathogenic factor for proliferative glomerulonephritis. We compared the potencies of the inhibitory effects of simvastatin acid, lovastatin acid, and pravastatin on fetal bovine serum (FBS)-induced proliferation of rat cultured mesangial cells, and examined the correlation between their inhibitory effects ...
