α, α??Dibromoketones: A Superior Alternative to α??Bromoketones in Hantzsch Thiazole Synthesis

R Prakash, A Kumar, R Aggarwal…

Index: Prakash, Richa; Kumar, Ajay; Aggarwal, Ranjana; Prakash, Om; Singh Synthetic Communications, 2007 , vol. 37, # 15 p. 2501 - 2505

Full Text: HTML

Citation Number: 27

Abstract

Abstract α, α??Dibromoketones (2) have been found to be a superior alternative to the conventionally used α??bromoketones (1) for performing the Hantzsch thiazole synthesis. 1 These crystalline, nonlachrymatory compounds are more reactive than 1 as demonstrated by their reaction with 3, 5??dimethyl??1??thiocarboxamide (5).