Journal of Chemical Research

A facile one-pot synthesis of 2-pyrazolyl-4-aryl-thiazoles in a three-component reaction

G Nalajam, RR Vedula

Index: Nalajam, Guravaiah; Vedula, Rajeswar Rao Journal of Chemical Research, 2008 , # 4 p. 195 - 197

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Citation Number: 5

Abstract

A one-pot multi-component reaction of phenacylbromide, thiosemicarbazide and acetyl acetone or ethyl acetoacetate is described for the preparation of the title compounds. The key features of this methodology are its operational simplicity, mild reaction conditions, and good yields.