Synthesis and alkylation of 5??(3??chlorobenzo [b] thien??2??yl)??4H??1, 2, 4??triazole??3??thiol under classical and microwave conditions. AM1 semiemperical calculations …

…, AA Kassem, H Abdel??Hamid, FF Louis…

Index: El Ashry; Kassem; Abdel-Hamid; Louis; Khattab; Aouad Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1421 - 1429

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Citation Number: 11

Abstract

Literature is enriched with progressive advances for the synthesis and pharmacological action of fused heterocycles. Those containing the benzo [b] thiophene nucleus are associated with diverse biological activities against inflammatory, analgesic [1, 2], microbial [3], and herbicidal [4] effects. Substituted-1, 2, 4-triazoles also have pharmacological properties including sedative, nicotine antagonistic, anticonvulsant [5-7] and antitumor [8] ...