Synthesis and biological activity of some more heterocyclic compounds containing benzothiophene moiety

…, P Thamyongkit, R Klai-U-dom…

Index: Naganagowda, Gadada; Thamyongkit, Patchanita; Klai-U-Dom, Runchana; Ariyakriangkrai, Waraporn; Luechai, Arithat; Petsom, Amorn Journal of Sulfur Chemistry, 2011 , vol. 32, # 3 p. 235 - 247

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Citation Number: 5

Abstract

3-Chloro-1-benzothiophene-2-carbonylchloride 1 was allowed to react with hydrazine hydrate to give carbohydrazide 2. The reaction of 3-chloro-1-benzothiophene-2- carbohydrazide 2 with potassium thiocyanate gave compound 3, which was cyclized to form thioxotetrahydropyrimidine 4, thiazoles 5a–e, triazoles 7a–e and oxadiazoles 10a–h. The structures of all the synthesized compounds were confirmed by spectral data and have ...