Synthesis and alkylation of 5??(3??chlorobenzo [b] thien??2??yl)??4H??1, 2, 4??triazole??3??thiol under classical and microwave conditions. AM1 semiemperical calculations …
Literature is enriched with progressive advances for the synthesis and pharmacological action of fused heterocycles. Those containing the benzo [b] thiophene nucleus are associated with diverse biological activities against inflammatory, analgesic [1, 2], microbial [3], and herbicidal [4] effects. Substituted-1, 2, 4-triazoles also have pharmacological properties including sedative, nicotine antagonistic, anticonvulsant [5-7] and antitumor [8] ...