New benzothiazines. 4. 1H-2, 3-Benzothiazin-4 (3H)-one 2, 2-dioxide and 2H-1, 2-benzothiazin-3 (4H)-one 1, 1-dioxide nitrogen derivatives with central nervous …

…, R Redaelli, MJ Magistretti, E Massarani

Index: Sianesi; Redaelli; Magistretti; Massarani Journal of Medicinal Chemistry, 1973 , vol. 16, # 10 p. 1133 - 1137

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Citation Number: 26

Abstract

This laboratory has been concerned with the preparation and pharmacological study of a number of 1, 2-, 2, 3-, and 2, l-benzothiazine S, S-dioxide derivatives. The sulfamyl group as a part of heterocyclic, particularly sixmembered, rings has long been recognized of great value, as, for example, in the 1, 2, 4-benzothiadiazine 1, l-dioxide series where, besides the well-known diuretic derivatives, others with antihypertensiveZ and/or hyperglycemic3 ...