Tetrahedron letters

Arachidonate epoxygenase: Total synthesis of both enantiomers of 8, 9-and 11, 12-epoxyricosatrienoic acid

P Mosset, P Yadagiri, S Lumin, J Capdevila, JR Falck

Index: Mosset, Paul; Yadagiri, Pendri; Lumin, Sun; Capdevila, Jorge; Falck, J. R. Tetrahedron Letters, 1986 , vol. 27, # 50 p. 6035 - 6038

Full Text: HTML

Citation Number: 31

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Both enantiomers of the epoxygenase metabolites 8,9- and 11,12-epoxyeicosatrienoic acid (EET) were synthesized by a convergent strategy utilizing dimethyl D- or L-malate and erythrospecific epoxidation. ... The epoxygenase metabolites 8,9- and 11,12-EET were prepared from ...

 Related Synthetic Route
Dimethyl malate Structure

617-55-0

Dimethyl malate

~%

(4S)-2,2-Dimethyl-1,3-Dioxolane-4-Acetaldehyde Structure

32233-44-6

(4S)-2,2-Dimeth...

11(S),12(R)-epoxyeicosatrienoic acid methyl ester Structure

90080-08-3

11(S),12(R)-epo...

~%

(11S,12R)-EET Structure

123931-40-8

(11S,12R)-EET

7-carbomethoxy hepta-3-(Z)-en-1-ylidenetriphenylphosphorane Structure

109296-17-5

7-carbomethoxy ...

~%

(11S,12R)-EET Structure

123931-40-8

(11S,12R)-EET

Phosphorane of (Z)-3-nonen-1-yl-triphenylphosponium bromide Structure

73958-09-5

Phosphorane of ...

~%

(11S,12R)-EET Structure

123931-40-8

(11S,12R)-EET


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