e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Stereoselective preparation of O-alkoxy d-tetrose, d-pentose, 2-deoxy-d-glycero tetrose and 2, 3-dideoxy-d-erythro pentose derivatives by an iterative elongation of 2, …
All d-pentoses are synthesized by one-carbon chain elongation commencing with the addition of the lithium salt of ethyl ethylthiomethyl sulfoxide to 2-O-(t-butyldimethylsilyl)-3, 4- O-isopropylidene-d-erythrose and d-threose, 16 and 17. The addition of the above- mentioned nucleophile to 2-deoxy-3, 4-O-isopropylidene-d-glycero tetrose, 19, gave rise to 2, 3-dideoxy-d-glycero pentose. The starting aldehydes, 16, 17 and 19, are easily ...
