Medicinal Chemistry Research

Synthesis and cytotoxicity of novel chrysin derivatives

K Hu, W Wang, H Cheng, SS Pan, J Ren

Index: Hu, Kun; Wang, Wei; Cheng, Hong; Pan, ShaSha; Ren, Jie Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 838 - 846

Full Text: HTML

Citation Number: 17

Abstract

Abstract A series of chrysin derivatives 8a–8v were prepared and tested in vitro against HCT- 116 (human colon cancer cell line), Hela (human cervical carcinoma cell line), DU-145 (human prostate cell line), K562 (human leukemia cell line), and SGC-7901 (human gastric cancer cell line). The chemical structures of these compounds were confirmed by means of MS, IR, 1 H NMR, 13 C NMR, and elemental analysis. Among these derivatives, 7-(2-( ...

An efficient synthesis of chrysin

[Liu, Man; Zhang, Ji; Yang, Jian; Yang, Bo; Cui, Wei Journal of Chemical Research, 2014 , vol. 38, # 3 p. 134 - 136]

An efficient one-pot synthesis of flavones

[Chee, Chin Fei; Buckle, Michael J.C.; Rahman, Noorsaadah Abd. Tetrahedron Letters, 2011 , vol. 52, # 24 p. 3120 - 3123]

Multifunctional tacrine–flavonoid hybrids with cholinergic, ...

[Li, Su-Yi; Wang, Xiao-Bing; Xie, Sai-Sai; Jiang, Neng; Wang, Kelvin D.G.; Yao, He-Quan; Sun, Hong-Bin; Kong, Ling-Yi European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 632 - 646]

Enzyme-catalyzed alcoholysis of flavone acetates in organic ...

[Natoli, Mariapina; Nicolosi, Giovanni; Piattelli, Mario Tetrahedron Letters, 1990 , vol. 31, # 50 p. 7371 - 7374]

Lewis Acid Triggered Regioselective Magnesiation and Zincati...

[Klier, Lydia; Bresser, Tomke; Nigst, Tobias A.; Karaghiosoff, Konstantin; Knochel, Paul Journal of the American Chemical Society, 2012 , vol. 134, # 33 p. 13584 - 13587]