Synthesis and rearrangement of methanesulfonate esters of N-hydroxyacetanilides. A model for a penultimate carcinogen

PG Gassman, JE Granrud

Index: Gassman, Paul G.; Granrud, John E. Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1498 - 1499

Full Text: HTML

Citation Number: 64

Abstract

I-acylarylnitrenium ion 3 as the ultimate electrophilic car~ inogen.~~~ Unfortunately, relatively little evidence exists for the heterolytic cleavage of the sulfonate esters of N- arylhydroxamic acids, primarily because previous attempts to prepare this class of compounds have led mostly to materials with rearranged structures. 5s6 We now wish to report on the synthesis, isolation, and characterization of a series of methanesulfonate ...

 Related Synthetic Route

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~%