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Synthesis and rearrangement of methanesulfonate esters of N-hydroxyacetanilides. A model for a penultimate carcinogen

PG Gassman, JE Granrud

文献索引:Gassman, Paul G.; Granrud, John E. Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1498 - 1499

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被引用次数: 64

摘要

I-acylarylnitrenium ion 3 as the ultimate electrophilic car~ inogen.~~~ Unfortunately, relatively little evidence exists for the heterolytic cleavage of the sulfonate esters of N- arylhydroxamic acids, primarily because previous attempts to prepare this class of compounds have led mostly to materials with rearranged structures. 5s6 We now wish to report on the synthesis, isolation, and characterization of a series of methanesulfonate ...

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