Letters in Drug Design & Discovery

Synthesis and Bio-Evaluation of Novel Salicylic Acid-Oriented Thiourea Derivatives with Potential Applications in Agriculture

S Li, H Li, X Cao, C Chen

Index: Li, Shaowei; Li, Huangyong; Cao, Xiufang; Chen, Changshui Letters in Drug Design and Discovery, 2014 , vol. 11, # 1 p. 98 - 103

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Citation Number: 2

Abstract

A series of salicylic acid-oriented thiourea derivatives was conveniently synthesized via multi-steps mainly including alkylation, chlorination, nucleophilic substitution and addition reaction. The structure of all these newly synthesized derivatives was confirmed and characterized by IR, 1H NMR and MS. The preliminary bioassay indicated that these new compounds have some herbicidal activity or plant growth regulating activity against tested ...