Journal of Heterocyclic Chemistry

A Novel and Efficient One Pot Synthesis of 2, 4??Disubstituted Thiazoles and Oxazoles Using Phenyltrimethylammoniumtribromide in Ionic Liquid

MK Muthyala, A Kumar

Index: Muthyala, Manoj Kumar; Kumar, Anil Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 959 - 964

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Citation Number: 5

Abstract

Abstract A novel and efficient one-pot procedure has been described for synthesis of 2, 4- disubstituted thiazoles and oxazoles from substituted ketones using phenyltrimethylammoniumtribromide as in situ brominating agent followed by reaction with thioamide/thiourea and amides/ureas, respectively in [bmim][BF 4] ionicliquid. The advantages of the procedure include avoiding the handling of lacrymetric compounds, ...

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