Chemistry letters

DNA Strand Scissions by Hydroxamic Acids-Copper (II) Ion under Aerobic Conditions.

S Hashimoto, R Yamashita, Y Nakamura

Index: Hashimoto, Shigeki; Yamashita, Rinichi; Nakamura, Yushin Chemistry Letters, 1992 , # 9 p. 1639 - 1642

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Citation Number: 17

Abstract

Carbazolyloxyacetohydroxamic acid (1), 9, 9′-decamethylene-bis- carbazolyloxyacetohydroxamic acid (2), benzohydroxamic acid (3) and acetohydroxamic acid (4) without reducing agent under aerobic conditions induced Col E1 DNA strand scissions with increasing of the activities in the order of 4> 3> 2> 1. Inhibition experiments indicated that hydrogen peroxide and superoxide participated in the reactions, but ...

N-Substituted carbazolyloxyacetic acids modulate Alzheimer a...

[Narlawar, Rajeshwar; Perez Revuelta, Blanca I.; Baumann, Karlheinz; Schubenel, Robert; Haass, Christian; Steiner, Harald; Schmidt, Boris Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 1 p. 176 - 182]

Novel carvedilol analogues that suppress store-overload-indu...

[Smith, Chris D.; Wang, Aixia; Vembaiyan, Kannan; Zhang, Jingqun; Xie, Cuihong; Zhou, Qiang; Wu, Guogen; Chen, S. R. Wayne; Back, Thomas G. Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8626 - 8655]