Tetrahedron

A novel isocyanide-based three-component reaction: a facile synthesis of substituted 2H-pyran-3, 4-dicarboxylates

MA Khalilzadeh, Z Hossaini, MM Baradarani…

Index: Khalilzadeh, Mohammad A.; Hossaini, Zinatossadat; Baradarani, Mohammad M.; Hasannia, Adel Tetrahedron, 2010 , vol. 66, # 43 p. 8464 - 8467

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Citation Number: 17

Abstract

An efficient method for synthesis of 2H-pyran-3, 4-dicarboxylates using the three-component reaction of dithiocarbamates, dialkyl acetylenedicarboxylates, and isocyanides in solvent- free conditions is described. In these reactions, synthesis of dithiocarbamates is possibly based on the one-pot reaction of secondary amines, CS2, and alkyl halides in solvent-free conditions without using a catalyst. The mild reaction conditions and high yields of the ...