CeCl3⊙ 7H2O-NaI Catalyzed Hydrooxacyclization of Unsaturated 3-Hydroxy Esters

…, E Foresti, T Marcelli, F Peri, P Righi, N Scardovi…

Index: Marotta, Emanuela; Foresti, Elisabetta; Marcelli, Tommaso; Peri, Francesca; Righi, Paolo; Scardovi, Noemi; Rosini, Goffredo Organic Letters, 2002 , vol. 4, # 25 p. 4451 - 4453

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Citation Number: 46

Abstract

Cerium (III) chloride heptahydrate and sodium iodide in boiling acetonitrile promote cyclization of 3-hydroxyalkenoic acids esters giving 5-substituted tetrahydrofuranacetic acid esters and 6-substituted tetrahydropyranacetic acid esters in fair to good yield and with complete retention of the absolute configuration of the starting 3-hydroxy ester.