General and Selective C??3 Alkylation of Indoles with Primary Alcohols by a Reusable Pt Nanocluster Catalyst

SMA Siddiki, K Kon, K Shimizu

Index: Siddiki, S. M. A. Hakim; Kon, Kenichi; Shimizu, Ken-Ichi Chemistry - A European Journal, 2013 , vol. 19, # 43 p. 14416 - 14419

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Citation Number: 19

Abstract

The indole scaffold is one of most relevant structures found in natural products, pharmaceuticals ingredients, functional materials and agro-chemicals.[1] C-3 substituted indoles are of particular importance for the construction of various biologically active molecules.[2–3] Conventional methodologies for the generation of C-3 substituted indoles require stoichiometric amount of Lewis acids, which have serious drawbacks such as poor ...