Journal of Organometallic Chemistry

Nickel-catalyzed, base-mediated amination/hydroamination reaction sequence for a modular synthesis of indoles

L Ackermann, W Song, R Sandmann

Index: Ackermann, Lutz; Song, Weifeng; Sandmann, Rene Journal of Organometallic Chemistry, 2011 , vol. 696, # 1 p. 195 - 201

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Citation Number: 31

Abstract

A catalytic system consisting of [Ni (cod) 2] and ligand dppf enabled an efficient synthesis of differently substituted indoles through a modular reaction sequence, which consists of intermolecular aminations and intramolecular hydroaminations with ortho- alkynylhaloarenes.