Tetrahedron letters

Facile routes to boron enolates. Et 3 B-mediated Reformatsky type reaction and three components coupling reaction of alkyl iodides, methyl vinyl ketone, and carbonyl …

K Nozaki, K Oshima, K Utimoto

Index: Nozaki, Kyoko; Oshima, Koichiro; Utimoto, Kiitiro Tetrahedron Letters, 1988 , vol. 29, # 9 p. 1041 - 1044

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Citation Number: 56

Abstract

Abstract Reaction of α-bromoketones with Ph 3 SnH in the presence of Et 3 B provides boron enolates which react with carbonyl compounds to give β-hydroxyketones in good yields. Et 3 B-induced Reformatsky type reaction of α-iodoketones with an aldehyde or ketone proceeds without Ph 3 SnH.