Biosynthesis of N-methylpelletierine: vindication of a classical biogenetic concept

T Hemscheidt, ID Spenser

Index: Hemscheidt, Thomas; Spenser, Ian D. Journal of the American Chemical Society, 1990 , vol. 112, # 17 p. 6360 - 6363

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Citation Number: 20

Abstract

Abstract: The 13C NMR spectrum of a sample of N-methylpelletierine (2), generated biosynthetically from sodium [1, 2, 3, 4-13C4] acetoacetate in Sedum sarmentosum Bunge, shows that the C3 side chain of the alkaloid is derived as an intact unit from the C4 precursor. The" C NMR spectrum of a sample of the alkaloid, biosynthetically derived from sodium [1, 2-I3C2] acetate, shows that it is the-COCH3 unit and not the-CH2CO-unit of the ...