Molecules

Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors

M Sechi, U Azzena, MP Delussu, R Dallocchio, A Dessì…

Index: Molecules, , vol. 13, # 10 p. 2442 - 2461

Full Text: HTML

Citation Number: 25

Abstract

... Volume. Page. ... On this basis, a new set of molecules with structures 3a-f (Figure 4) was designed and synthesized considering a) bulkiness of substituents, and b) the substitution of an amidic motif with a hydrazidic one, hopefully suitable for coordination with ... Molecular Modeling. ...