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Molecules

Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors

M Sechi, U Azzena, MP Delussu, R Dallocchio, A Dessì…

文献索引:Molecules, , vol. 13, # 10 p. 2442 - 2461

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被引用次数: 25

摘要

... Volume. Page. ... On this basis, a new set of molecules with structures 3a-f (Figure 4) was designed and synthesized considering a) bulkiness of substituents, and b) the substitution of an amidic motif with a hydrazidic one, hopefully suitable for coordination with ... Molecular Modeling. ...