First Generation Cysteine??and Methionine??Derived Oxazolidine and Thiazolidine Ligands for Palladium??Catalyzed Asymmetric Allylations

…, CC Silveira, LA Wessjohann, AL Braga

Index: Schneider, Paulo H.; Schrekker, Henri S.; Silveira, Claudio C.; Wessjohann, Ludger A.; Braga, Antonio L. European Journal of Organic Chemistry, 2004 , # 12 p. 2715 - 2722

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Citation Number: 24

Abstract

Abstract A new series of enantiopure oxazolidine-thioether and thiazolidine-alcohol ligands have been synthesized from L-cysteine, S-methyl-L-cysteine, and L-methionine in a straightforward manner that allows numerous structural variations to be formed. These types of ligands have not previously been used in asymmetric palladium-catalyzed allylations and their efficacy was explored in the reaction of rac-1, 3-diphenyl-2-propenyl acetate with ...