Bifunctional bis (oxazolines) as potential ligands in catalytic asymmetric reactions

S Hanessian, E Jnoff, N Bernstein…

Index: Hanessian, Stephen; Jnoff, Eric; Bernstein, Noemy; Simard, Michel Canadian Journal of Chemistry, 2004 , vol. 82, # 2 p. 306 - 313

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Citation Number: 12

Abstract

C 2-symmetrical bis (oxazoline) ligands bearing pendant alkylthio ether groups were synthesized, and the structures of Cu complexes were determined by single crystal X-ray diffraction. The potential utility in catalysis was shown in the asymmetric addition of methyllithium to an aromatic aldimine, which resulted in a mixture of products with an enantiomeric excess of 68%. Key words: two-center catalysis, bis (oxazoline), aldimine, ...