S-Methyl-L-cysteine

Modify Date: 2025-08-21 18:06:30

S-Methyl-L-cysteine Structure
S-Methyl-L-cysteine structure
 Common Name S-Methyl-L-cysteine
CAS Number 1187-84-4 Molecular Weight 135.185
Density 1.2±0.1 g/cm3 Boiling Point 242.8±30.0 °C at 760 mmHg
Molecular Formula C4H9NO2S Melting Point ~240 °C (dec.)
MSDS Chinese USA Flash Point 100.7±24.6 °C

 Use of S-Methyl-L-cysteine


S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities.

 Names

Name S-methyl-L-cysteine
Synonym More Synonyms

 S-Methyl-L-cysteine Biological Activity

Description S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities.
Related Catalog
In Vivo S-Methyl-L-cysteine (100 mg/kg) results in significant attenuation of plasma glucose, insulin, tumor necrosis factor-alpha, insulin resistance and improved antioxidant enzyme activities[1].
References

[1]. Thomas S, et al. Effect of s-methyl-L-cysteine on oxidative stress, inflammation and insulin resistance in male wistar rats fed with high fructose diet. Iran J Med Sci. 2015 Jan;40(1):45-50.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 242.8±30.0 °C at 760 mmHg
Melting Point ~240 °C (dec.)
Molecular Formula C4H9NO2S
Molecular Weight 135.185
Flash Point 100.7±24.6 °C
Exact Mass 135.035400
PSA 88.62000
LogP 0.47
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.509
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S22-S24/25-S36/37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles34

More Articles
Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer.

PLoS ONE 10 , e0127063, (2015)

Expression of matrix metalloproteinase 9 (MMP9) is elevated in a variety of inflammatory and oncology indications, including ulcerative colitis and colorectal cancer. MMP9 is a downstream effector and...

Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes.

Pharmazie 70 , 678-83, (2015)

Although chemical trapping has been widely used to evaluate cytochrome P450-mediated drug bioactivation, thus far, only a few in vitro-trapping studies have been performed on UDP-glucuronosyltransfera...

Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Bioorg. Med. Chem. Lett. 17 , 3921-4, (2007)

Inhibition of Eg5 represents a novel approach for the treatment of cancer. Here, we report the synthesis and structure-activity relationship of S-trityl-L-cysteine (STLC) derivatives as Eg5 inhibitors...

 Synonyms

L-methylcysteine
(2R)-2-(Methylamino)-3-sulfanylpropanoic acid
S-METHYL-CYSTEINE
H-Cys(Me)-OH
SMC
Methylcysteine
DL-S-Methyl-cysteine
N-Methyl-L-cystein
Cysteine, N-methyl, L-
(R)-N-Methylcysteine
S-Methyl-L-cysteine
(2R)-2-amino-3-methylsulfanyl-propionic acid
EINECS 214-701-6
L-Cysteine, N-methyl-
L-Cysteine,S-methyl
N-Méthyl-L-cystéine
L-CH3SCH2CH(NH2)COOH
N-Methyl-L-cysteine
H-L-CYS(ME)-OH
MFCD00002612
(R)-2-Amino-3-(methylmercapto)propionic acid SMLC
S-Methyl-L-Cys-OH
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Chemsrc provides S-Methyl-L-cysteine(CAS#:1187-84-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of S-Methyl-L-cysteine are included as well.>> amp version: S-Methyl-L-cysteine

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