Journal of combinatorial chemistry

One-pot synthesis of five and six membered N, O, S-heterocycles using a ditribromide reagent

R Yella, BK Patel

Index: Yella, Ramesh; Patel, Bhisma K. Journal of Combinatorial Chemistry, 2010 , vol. 12, # 5 p. 754 - 763

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Citation Number: 26

Abstract

In a one-pot procedure, bromine less brominating reagent 1, 1′-(ethane-1, 2-diyl) dipyridinium bistribromide (EDPBT) has been utilized as an efficient desulfurizing agent for the construction of a library of heterocycles containing N, O, and S starting from aryl/alkyl isothiocyanates. In this approach, aryl/alkyl isothiocyanate reacts with o-phenylenediamine (o-PD), o-aminophenol, and o-aminothiophenol to form their monothiourea which on ...