Quinazoline derivatives have attracted considerable attention due to their significant biological activities [1, 2], especially antifungal [3, 4], insecticidal [5], antihistaminic [6], anti- inflammatory [7], antibacterial [8], anticonvulsant [9, 10], antithrombotic [11], antitubercular [12], and antitumor [13]. In this article, we report a new route for the synthesis of triazolo and tetracyclic derivatives of quinazolinone.