Tetrahedron

Antimicrobial indolequinones from the mid-intestinal gland of the muricid gastropod Drupella fragum

…, C Iwatsuki, M Kodama, M Ochi, K Kataoka, K Shibata

Index: Fukuyama, Yoshiyasu; Iwatsuki, Chie; Kodama, Mitsuaki; Ochi, Masamitsu; Kataoka, Kumi; Shibata, Kozo Tetrahedron, 1998 , vol. 54, # 34 p. 10007 - 10016

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Citation Number: 39

Abstract

Three new indolequinones, 6-methoxyindole-4, 7-quinone (1), 5-methoxyindole-4, 7- quinone (2) and 5-methylindole-4, 7-quinone (3) were isolated from the mid-intestinal gland of the muricid gastropod Drupella fragum. The structures of 1 and 2 were established by spectroscopic methods and total synthesis, whereas the structure of 3 was elucidated mainly by NMR spectroscopic analyses. Compounds 1∼ 3 exhibited moderate antimicrobial ...