Synthesis and adrenolytic activity of 1-(1H-indol-4-yloxy)-3-(2-(2-methoxy phenoxy) ethylamino) propan-2-ol analogs and its enantiomers. Part 2

…, A Nowak-Król, T Wdowik, D Świerczyński…

Index: Groszek, Grazyna; Nowak-Krol, Agnieszka; Wdowik, Tomasz; Swierczynski, Dariusz; Bednarski, Marek; Otto, Monika; Walczak, Maria; Filipek, Barbara European Journal of Medicinal Chemistry, 2009 , vol. 44, # 12 p. 5103 - 5111

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Citation Number: 11

Abstract

The synthesis of (2RS)-1-(5-methoxy-1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy) ethylamino) propan-2-ol and (2RS)-1-(7-methoxy-1H-indol-4-yloxy)-3-(2-(2- methoxyphenoxy) ethylamino) propan-2-ol and its enantiomers, analogs of 1-(1H-indol-4- yloxy)-3-(2-(2-methoxyphenoxy) ethylamino) propan-2-ol ((RS)-9) is described. Compounds were tested for electrographic, antiarrhythmic, hypotensive and spasmolytic activities as ...