Abstract: Cell-free enzymes from Gibberella fujikuroi convert farnesyl pyrophosphate (1) to nerolidyl pyrophosphate (2) and thence to cyclonerodiol (3) by way of cyclonerodiol pyrophosphate. This pathway is supported by incubation and degradation experiments, competitive incubation studies, trapping and degradation of nerolidyl pyrophosphate, and direct I3C NMR observation of the enzymatic conversion of nerolidyl pyrophosphate to ...
