Synthesis of new 4??quinolone??type compounds in the benzo [b] thiophene series

B Fevrier, G Dupas, J Bourguignon…

Index: Fevrier; Dupas; Bourguignon; Queguiner Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 1085 - 1088

Full Text: HTML

Citation Number: 13

Abstract

Abstract Some new derivatives of 1, 4-dihydro-4-oxo-3-pyridinecarboxylic acid (quinolone- type compounds) 5 and 13 have been prepared in the benzo [b] thiophene series. The key step was the construction of the pyridine ring starting from 2-aminobenzo [b] thiophene derivatives. The synthesis of amine 9, was performed by using an original “animation” reaction.