C 17, 20-Lyase inhibitors I. Structure-based de novo design and SAR study of C 17, 20-lyase inhibitors

N Matsunaga, T Kaku, F Itoh, T Tanaka, T Hara…

Index: Bioorganic and medicinal chemistry, , vol. 12, # 9 p. 2251 - 2273

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Citation Number: 40

Abstract

... Bioorganic & Medicinal Chemistry. ... a Medicinal Chemistry Research Laboratories ... At present, the standard treatment includes orchidectomy and its medical equivalent, the administration of gonadotropin-releasing hormone (GnRH) analogues, which abolish the production of ...