Abstract 2-Quinazolinepropionic acids have been obtained from the reactions of potassium cyanide with o-carboxy-or o-acyl-3-chloropropionanilides. Some of these compounds have been cyclized to pyrrolo [1, 2-a] quinazolines. The reaction of an o-carbethoxy-2- chloroacetanilide with potassium thiocyanate formed a 2-quinazolinylthioacetic acid, which was cyclized to a thiazolo-[3, 2-a] quinazoline. A mechanism is presented for the formation ...