Archiv der Pharmazie

Intramolekulare Aromatenalkylierungen, 22. Mitt. Synthese von cis??1, 6, 10??Trimethyl??1, 2, 3, 4, 5, 6, 7, 8, 9, 10??decahydroindolo (4, 3??fg) chinolin, ein neuer Zugang …

E Reimann, E Hargasser

Index: Reimann; Hargasser Archiv der Pharmazie, 1988 , vol. 321, # 11 p. 823 - 826

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Citation Number: 3

Abstract

Abstract Die aus den Indolaldehyden 5 und Brompicolin 6 bequem zugänglichen Carbinole 7 sind direkt oder als Ether 8 zu den Lutidinylindolen 9 hydrogenolysierbar. Das N- stellungsisomere Keton 17 ist nach Grignard aus 16 und dem gemischten Anhydrid 15,

~93%

~84%

INDQ/NO, a bioreductively activated nitric oxide prodrug

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