The Adamantyl Group in Medicinal Agents. IV. Sedative Action of 3, 5, 7-Trimethyladamantane-1-carboxamide1 and Related Agents

K Gerzon, DJ Tobias, RE Holmes…

Index: Journal of medicinal chemistry, , vol. 10, # 4 p. 603 - 606

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Citation Number: 27

Abstract

... 603 The Adamantyl Group in Medicinal Agents. ... Chemistry.-For the preparation of the necessary quantities of 1,3,5-trimethyladaniantane, the dlBr3- catalyzed rearrangement of perhydrofl~orene ... 100 ml), a solution of 3,5,7-trimethyladamantan-l-o1 (4.9 g) and pyridine (10 ml) in ...