Convenient Synthesis of Arylboronates through a Synergistic Pd/Cu??Catalyzed Miyaura Borylation Reaction under Atmospheric Conditions

J Ratniyom, N Dechnarong, S Yotphan…

Index: Ratniyom, Jadsada; Dechnarong, Nattanee; Yotphan, Sirilata; Kiatisevi, Supavadee European Journal of Organic Chemistry, 2014 , vol. 2014, # 7 p. 1381 - 1385

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Citation Number: 3

Abstract

Abstract A highly efficient and practical borylation reaction of aryl iodides with bis (pinacolato) diboron has been established. By using Pd (OAc) 2, CuI, and PPh 3 as a ligand at room temperature under air in the presence of Cs 2 CO 3, the protocol proved to be general. Various functionalized arylboronates were obtained in moderate to excellent yields. In addition, a possible reaction mechanism was proposed.