New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: Biological evaluation and structure–activity relationships

M Bollini, JJ Casal, DE Alvarez, L Boiani…

Index: Bioorganic and Medicinal Chemistry, , vol. 17, # 4 p. 1437 - 1444

Full Text: HTML

Citation Number: 29

Abstract

... Bioorganic & Medicinal Chemistry. ... cells, compound 2 may decrease GSH levels irreversibly because TR is unable to reduce GSSG effectively, although another possibility is that GSSG might deplete T(SH) 2 , Tryparedoxin (Tpx), and/or TR as a result of chemical 21 or ...

Synthesis of New Enantiopure Thioureas Derived from (S)-Prol...

[Wroblewska, Aneta; Mloston, Grzegorz Phosphorus, Sulfur and Silicon and the Related Elements, 2013 , vol. 188, # 4 p. 509 - 511]

A general and facile one-pot process of isothiocyanates from...

[Sun, Nan; Li, Bin; Shao, Jianping; Mo, Weimin; Hu, Baoxiang; Shen, Zhenlu; Hu, Xinquan Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 61 - 70]

Rhodium-catalyzed synthesis of isothiocyanate from isonitril...

[Arisawa, Mieko; Ashikawa, Masanori; Suwa, Atsushi; Yamaguchi, Masahiko Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1727 - 1729]

A facile one-pot preparation of isothiocyanates from N-forma...

[Shan; Bian; Su; Liang Organic Preparations and Procedures International, 2004 , vol. 36, # 3 p. 283 - 286]

Isothiocyanates from tosyl chloride mediated decomposition o...

[Journal of Organic Chemistry, , vol. 72, # 10 p. 3969 - 3971]