A Practical and Convenient Method for the Synthesis of Some Benzimidazoles

B Kaboudin, M Khodamorady…

Index: Kaboudin, Babak; Khodamorady, Minoo; Abedi, Yaghoub Organic Preparations and Procedures International, 2013 , vol. 45, # 2 p. 162 - 167

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Abstract

Benzimidazole and its derivatives represent an important class of bioactive molecules. 1 Some benzimidazoles are potent antiparasitic agents, 2 topoisomerase I inhibitors, 3 selective neuropeptide Y Y1 receptor antagonists, 4 angiotensin II (AII) inhibitors, 5 inhibitors of human cytomegalovirus (HCMV) replication, 6 potential antitumour agents, 7 antimicrobial agents, 8 and inhibitors of the hepatitis C virus RNA polymerase. 9 They have also shown ...