Benzimidazole and its derivatives represent an important class of bioactive molecules. 1 Some benzimidazoles are potent antiparasitic agents, 2 topoisomerase I inhibitors, 3 selective neuropeptide Y Y1 receptor antagonists, 4 angiotensin II (AII) inhibitors, 5 inhibitors of human cytomegalovirus (HCMV) replication, 6 potential antitumour agents, 7 antimicrobial agents, 8 and inhibitors of the hepatitis C virus RNA polymerase. 9 They have also shown ...
[Grobler, Ilne; Smith, Vincent J.; Bhatt, Prashant M.; Herbert, Simon A.; Barbour, Leonard J. Journal of the American Chemical Society, 2013 , vol. 135, # 17 p. 6411 - 6414]