e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Nucleophilicity Parameters of Pyridinium Ylides and Their Use in Mechanistic Analyses

DS Allgäuer, P Mayer, H Mayr

Index: Wang, Qi-Fang; Hui, Li; Hou, Hong; Yan, Chao-Guo Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 260 - 265

Full Text: HTML

Citation Number: 24

Abstract

... Journal of the ... 40), pp 15216–15224. DOI: 10.1021/ja407885h. Publication Date (Web): September 10, 2013. Copyright © 2013 American Chemical Society. ... Pyridinium ylides are readily accessible nucleophiles and their chemistry has been studied intensively.(1-6) They undergo ...

Pyridine Structure

Meldrumic acid Structure

4-Chlorobenzaldehyde Structure

4-Chlorobenzaldehyde

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Chlorobenzaldehyde Structure

4-Chlorobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

4-Chlorobenzaldehyde Structure

4-Chlorobenzaldehyde

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

4-Chlorobenzaldehyde Structure

4-Chlorobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

methylimidazole Structure

methylimidazole

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Methoxybenzaldehyde Structure

4-Methoxybenzal...

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Methoxybenzaldehyde Structure

4-Methoxybenzal...

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

4-Picoline Structure

Meldrumic acid Structure

4-Methoxybenzaldehyde Structure

4-Methoxybenzal...

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

4-Methoxybenzaldehyde Structure

4-Methoxybenzal...

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

4-Methoxybenzaldehyde Structure

4-Methoxybenzal...

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

2-picoline Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

4-Picoline Structure

Meldrumic acid Structure

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

4-Picoline Structure

Meldrumic acid Structure

4-Methoxybenzaldehyde Structure

4-Methoxybenzal...

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

4-Picoline Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

p-Tolualdehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Isoquinoline Structure

Meldrumic acid Structure

p-Tolualdehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Isoquinoline Structure

Meldrumic acid Structure

3-Nitrobenzaldehyde Structure

3-Nitrobenzaldehyde

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Isoquinoline Structure

Meldrumic acid Structure

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Isoquinoline Structure

Meldrumic acid Structure

4-Bromobenzaldehyde Structure

4-Bromobenzaldehyde

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Pyridine Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

ethyl 2-bromoacetate Structure

ethyl 2-bromoacetate

~%

Detail

Pyridine Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Pyridine Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

2-picoline Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

methylimidazole Structure

methylimidazole

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

3-Mepy Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

3-Mepy Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

p-Tolualdehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

3-Nitrobenzaldehyde Structure

3-Nitrobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

Benzaldehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Methoxybenzaldehyde Structure

4-Methoxybenzal...

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

3-Chlorobenzaldehyde Structure

3-Chlorobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Bromobenzaldehyde Structure

4-Bromobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Ethylbenzaldehyde Structure

4-Ethylbenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Isopropylbenzaldehyde Structure

4-Isopropylbenz...

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

p-Tolualdehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

4-Chlorobenzaldehyde Structure

4-Chlorobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

Benzaldehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

1,3-dimethylbarbituric acid Structure

1,3-dimethylbar...

4-Bromobenzaldehyde Structure

4-Bromobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

m-Tolualdehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

Benzaldehyde Structure

ethyl 2-bromoacetate Structure

ethyl 2-bromoacetate

~%

Detail

Pyridine Structure

Meldrumic acid Structure

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Pyridine Structure

Meldrumic acid Structure

Benzaldehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

4-Picoline Structure

Meldrumic acid Structure

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Isoquinoline Structure

Meldrumic acid Structure

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

Benzaldehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

Benzaldehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

4-Chlorobenzaldehyde Structure

4-Chlorobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

m-Tolualdehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Meldrumic acid Structure

p-Tolualdehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Pyridine Structure

Meldrumic acid Structure

p-Tolualdehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Isoquinoline Structure

Meldrumic acid Structure

p-Tolualdehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

p-Tolualdehyde Structure

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

p-Tolualdehyde Structure

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

4-Nitrobenzaldehyde Structure

4-Nitrobenzaldehyde

2-Bromoacetophenone Structure

2-Bromoacetophenone

~%

Detail

Meldrumic acid Structure

3-Mepy Structure

4-Nitrobenzaldehyde Structure

4-Nitrobenzaldehyde

4-nitrobenzylbromide Structure

4-nitrobenzylbromide

~%

Detail

Pyridine Structure

Barbituric acid Structure

Barbituric acid

Benzaldehyde Structure

ethyl 2-bromoacetate Structure

ethyl 2-bromoacetate

~%

Detail

Organic reactions in ionic liquids: ionic liquid ethylammoni...

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Synthesis of 5-arylidene-2, 2-dimethyl-1, 3-dioxane-4, 6-dio...

[Kumar, Dhruva; Suresh; Sandhu, Jagir S. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 8 p. 1157 - 1160]

Modular synthesis of tetrahydrofluorenones from 5-alkylidene...

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