Synthesis and Characterization of Some Heteroaromatic Derivatives of 3??But??2??enoyl??chromen??2??one and Their Potential as Anti??inflammatory Agents

P Dixit, AC Tripathi, SK Saraf

Index: Dixit, Priyanka; Tripathi, Avinash C.; Saraf, Shailendra K. Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 6 p. 1431 - 1436

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Abstract

Abstract A novel series of chromen-2-ones containing pyrazole, isoxazole, oxazine, and thiazine substitutions have been synthesized by reacting 3-[3-(4-chloro-phenyl)-acryloyl]- chromen-2-one and 3-[3-(3-methoxy-phenyl)-acryloyl]-chromen-2-one with various cyclizing agents such as hydrazine, phenylhydrazine, urea, and thiourea. The structures of all the synthesized compounds were confirmed by the use of IR, 1 H-NMR, mass spectroscopy, ...