Total syntheses of natural furan derivatives rehmanones A, B, and C

H Quiroz-Florentino, R Aguilar, BM Santoyo, F Díaz…

Index: Quiroz-Florentino, Hector; Aguilar, Raul; Santoyo, Blanca M.; Diaz, Francisco; Tamariz, Joaquin Synthesis, 2008 , # 7 p. 1023 - 1028

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Citation Number: 6

Abstract

Abstract The synthesis of naturally occurring furan derivatives rehmanones A, B, and C is described. Diverse alternative synthetic strategies were developed for the preparation of these natural products. Conjugate addition of a furan to captodative alkene 1-acetylvinyl 4- nitrobenzoate was carried out under Lewis acid catalysis to give the corresponding adduct, which was transformed into rehmanones B and C in three and two steps, respectively. ...