Organic & biomolecular chemistry

Thiourea dioxide promoted efficient organocatalytic one-pot synthesis of a library of novel heterocyclic compounds

S Verma, S Kumar, SL Jain, B Sain

Index: Verma, Sanny; Kumar, Subodh; Jain, Suman L.; Sain, Bir Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 6943 - 6948

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Citation Number: 42

Abstract

The utility of thiourea dioxide as an efficient organocatalyst for the library synthesis of novel heterocyclic compoundsvia one-pot multicomponent coupling reactions is disclosed. Thiourea dioxide is an inexpensive and readily accessible catalyst, resulting in better product yields as compared to the corresponding thiourea as catalyst. Thiourea dioxide is found to be insoluble in various organic solvents and therefore at the end of the reaction ...