An Efficient Synthesis of 2??Substituted Benzoxazoles via RuCl3· 3H2O Catalyzed Tandem Reactions in Ionic Liquid

…, Y He, Y Wang, X Zhang, J Wang

Index: Fan, Xuesen; He, Yan; Wang, Yangyang; Zhang, Xinying; Wang, Jianji Chinese Journal of Chemistry, 2011 , vol. 29, # 4 p. 773 - 777

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Citation Number: 9

Abstract

Abstract An efficient synthesis of 2-substituted benzoxazoles through RuCl 3· 3H 2 O catalyzed, air oxidized tandem reactions of 2-aminophenols and aldehydes in [bmim] BF 4 was developed. This synthetic strategy has such advantages as mild reaction conditions, cost-free oxidant, readily available starting materials, and recyclable catalyst and solvent. As an application, it was successfully used in the synthesis of the unreported 5-(benzoxazol-2 ...