Synthesis of 2??Arylbenzoxazoles through Oxidation of C–H Bonds Adjacent to Oxygen Atoms

L Gu, W Wang, Y Xiong, X Huang…

Index: Gu, Lijun; Wang, Wei; Xiong, Yong; Huang, Xiangzhong; Li, Ganpeng European Journal of Organic Chemistry, 2014 , vol. 2014, # 2 p. 319 - 322

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Citation Number: 7

Abstract

Benzoxazoles are an important class of nitrogen-containing heterocycles, as they are the basic constituents of numerous natural products, biologically active alkaloids, and pharmaceuticals.1 These compounds have been extensively studied for their biological and therapeutic activities. They have been shown to act as cathepsin inhibitors, topoisomerase II inhibitors, and PTP-1B inhibitors. In addition, substituted benzoxazoles are increasingly ...