Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase

J Ohkanda, CL Strickland, MA Blaskovich…

Index: Organic and Biomolecular Chemistry, , vol. 4, # 3 p. 482 - 492

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Citation Number: 13

Abstract

... Results and discussion. Chemistry. ... Chemical shifts were reported in δ (ppm) relative to tetramethylsilane. All coupling constants were described in Hz. ... Flash column chromatography was performed on silica gel (40–63 µm) under a pressure of about 4 psi. ...

~10%

~12%

Practical multigram synthesis for 4 (5)-vinylimidazole

[Kokosa, John M.; Szafasz, Richard A.; Tagupa, Eumar Journal of Organic Chemistry, 1983 , vol. 48, # 20 p. 3605 - 3607]

Synthesis of L??histidine specifically labelled with stable ...

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Synthesis of 4 (5)-acyl-, 1-substituted 5-acyl-and 1-substit...

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The chemical simulation of the “atp-imidazole” cycle

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Novel N-(4-piperidinyl) benzamide antimalarials with mammali...

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