Tetrahedron

The chemical simulation of the “atp-imidazole” cycle

…, F Farooqui, D Bhattacharyya, S Mehrotra, K Kesavan

Index: Ranganathan, Darshan; Farooqui, Firdous; Bhattacharyya, Diphti; Mehrotra, Sanjiv; Kesavan, K. Tetrahedron, 1986 , vol. 42, # 16 p. 4481 - 4492

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Citation Number: 14

Abstract

The synthetic strategy inherent in the “ATP-Imidazole” cycle and centred around the vicinal disposition of-NH2 and-CONH2 functions, has been demonstrated with anthranilamide (2) and 1-benzyl-5-aminoimidazole-4-carboxamide (1) as regeneratable carriers involving specifically N-alkylated quinazolin-4-ones, hypoxanthines and adenines, as key intermediates. The isolation and characterization of the enamine (22) coupled with other ...