Improved Process for Ranolazine: An Antianginal Agent†

S Aalla, G Gilla, RR Anumula, S Kurella…

Index: Organic Process Research and Development, , vol. 16, # 5 p. 748 - 754

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Citation Number: 5

Abstract

... Organic Process Research & Development. ... 2.2New Process Conditions for Piperazine Derivative 6 Synthesis of piperazine derivative 6 involves N-alkylation of piperazine (5) with compound 4. Most of the reported processes for the preparation of 6 involve the use of ethanol ...