Tetrahedron

An expedient esterification of aromatic carboxylic acids using sodium bromate and sodium hydrogen sulfite

KM Khan, GM Maharvi, S Hayat, MI Choudhary

Index: Khan, Khalid Mohammed; Maharvi, Ghulam Murtaza; Hayat, Safdar; Zia-Ullah; Choudhary, M. Iqbal; Atta-ur-Rahman Tetrahedron, 2003 , vol. 59, # 29 p. 5549 - 5554

Full Text: HTML

Citation Number: 40

Abstract

Treatment of aromatic carboxylic acids and substituted toluenes with a mixture of sodium bromate and sodium hydrogen sulfite in a two-phase system gave the corresponding esters in good yield. The intermediate α-brominated toluene was formed by the in situ generated hypobromous acid. The α-bromotoluene underwent an intermolecular nucleophilic substitution reaction with aromatic carboxylic acids present in the reaction mixture to afford ...